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Pharmacological Characterization of the Mechanisms Involved in Delayed Calcium Deregulation in SH-SY5Y Cells Challenged with Methadone

Previously, we have shown that SH-SY5Y cells exposed to high concentrations of methadone died due to a necrotic-like cell death mechanism related to delayed calcium deregulation (DCD). In this study, we show that, in terms of their Ca(2+) responses to 0.5 mM methadone, SH-SY5Y cells can be pooled in...

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Detalles Bibliográficos
Autores principales: Perez-Alvarez, Sergio, Solesio, Maria E., Cuenca-Lopez, Maria D., Melero-Fernández de Mera, Raquel M., Villalobos, Carlos, Kmita, Hanna, Galindo, Maria F., Jordán, Joaquin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385639/
https://www.ncbi.nlm.nih.gov/pubmed/22778742
http://dx.doi.org/10.1155/2012/642482