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Assessment of 5-HT(7) Receptor Agonists Selectivity Using Nociceptive and Thermoregulation Tests in Knockout versus Wild-Type Mice

No study has ever examined the effect of 5-HT(7) receptor agonists on nociception by using 5-HT(7) receptor knockout mice. Basal sensitivity to noxious heat stimuli and formalin-induced nociception in both phase I and II of the formalin test did not differ in 5-HT(7) receptor knockout mice and paire...

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Detalles Bibliográficos
Autores principales: Brenchat, Alex, Rocasalbas, Maria, Zamanillo, Daniel, Hamon, Michel, Vela, José Miguel, Romero, Luz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385710/
https://www.ncbi.nlm.nih.gov/pubmed/22761612
http://dx.doi.org/10.1155/2012/312041