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Assessment of 5-HT(7) Receptor Agonists Selectivity Using Nociceptive and Thermoregulation Tests in Knockout versus Wild-Type Mice
No study has ever examined the effect of 5-HT(7) receptor agonists on nociception by using 5-HT(7) receptor knockout mice. Basal sensitivity to noxious heat stimuli and formalin-induced nociception in both phase I and II of the formalin test did not differ in 5-HT(7) receptor knockout mice and paire...
Autores principales: | Brenchat, Alex, Rocasalbas, Maria, Zamanillo, Daniel, Hamon, Michel, Vela, José Miguel, Romero, Luz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385710/ https://www.ncbi.nlm.nih.gov/pubmed/22761612 http://dx.doi.org/10.1155/2012/312041 |
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