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HLA-C and HIV-1: friends or foes?

The major histocompatibility complex class I protein HLA-C plays a crucial role as a molecule capable of sending inhibitory signals to both natural killer (NK) cells and cytotoxic T lymphocytes (CTL) via binding to killer cell Ig-like receptors (KIR). Recently HLA-C has been recognized as a key mole...

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Detalles Bibliográficos
Autores principales: Zipeto, Donato, Beretta, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386009/
https://www.ncbi.nlm.nih.gov/pubmed/22571741
http://dx.doi.org/10.1186/1742-4690-9-39