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Abnormal increase in urinary aquaporin-2 excretion in response to hypertonic saline in essential hypertension

BACKGROUND: Dysregulation of the expression/shuttling of the aquaporin-2 water channel (AQP2) and the epithelial sodium channel (ENaC) in renal collecting duct principal cells has been found in animal models of hypertension. We tested whether a similar dysregulation exists in essential hypertension....

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Detalles Bibliográficos
Autores principales: Graffe, Carolina Cannillo, Bech, Jesper Nørgaard, Lauridsen, Thomas Guldager, Vase, Henrik, Pedersen, Erling Bjerregaard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386017/
https://www.ncbi.nlm.nih.gov/pubmed/22452789
http://dx.doi.org/10.1186/1471-2369-13-15