Determination of minimal transcriptional signatures of compounds for target prediction

The identification of molecular target and mechanism of action of compounds is a key hurdle in drug discovery. Multiplexed techniques for bead-based expression profiling allow the measurement of transcriptional signatures of compound-treated cells in high-throughput mode. Such profiles can be used t...

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Detalles Bibliográficos
Autores principales: Nigsch, Florian, Hutz, Janna, Cornett, Ben, Selinger, Douglas W, McAllister, Gregory, Bandyopadhyay, Somnath, Loureiro, Joseph, Jenkins, Jeremy L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386022/
https://www.ncbi.nlm.nih.gov/pubmed/22574917
http://dx.doi.org/10.1186/1687-4153-2012-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386022/
https://www.ncbi.nlm.nih.gov/pubmed/22574917
http://dx.doi.org/10.1186/1687-4153-2012-2

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