Cargando…

Posterior Association Networks and Functional Modules Inferred from Rich Phenotypes of Gene Perturbations

Combinatorial gene perturbations provide rich information for a systematic exploration of genetic interactions. Despite successful applications to bacteria and yeast, the scalability of this approach remains a major challenge for higher organisms such as humans. Here, we report a novel experimental...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xin, Castro, Mauro A., Mulder, Klaas W., Markowetz, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386165/
https://www.ncbi.nlm.nih.gov/pubmed/22761558
http://dx.doi.org/10.1371/journal.pcbi.1002566