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Posterior Association Networks and Functional Modules Inferred from Rich Phenotypes of Gene Perturbations
Combinatorial gene perturbations provide rich information for a systematic exploration of genetic interactions. Despite successful applications to bacteria and yeast, the scalability of this approach remains a major challenge for higher organisms such as humans. Here, we report a novel experimental...
Autores principales: | Wang, Xin, Castro, Mauro A., Mulder, Klaas W., Markowetz, Florian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386165/ https://www.ncbi.nlm.nih.gov/pubmed/22761558 http://dx.doi.org/10.1371/journal.pcbi.1002566 |
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