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Deceleration of Fusion–Fission Cycles Improves Mitochondrial Quality Control during Aging

Mitochondrial dynamics and mitophagy play a key role in ensuring mitochondrial quality control. Impairment thereof was proposed to be causative to neurodegenerative diseases, diabetes, and cancer. Accumulation of mitochondrial dysfunction was further linked to aging. Here we applied a probabilistic...

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Detalles Bibliográficos
Autores principales: Figge, Marc Thilo, Reichert, Andreas S., Meyer-Hermann, Michael, Osiewacz, Heinz D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386171/
https://www.ncbi.nlm.nih.gov/pubmed/22761564
http://dx.doi.org/10.1371/journal.pcbi.1002576