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Interplay between Synaptonemal Complex, Homologous Recombination, and Centromeres during Mammalian Meiosis

The intimate synapsis of homologous chromosome pairs (homologs) by synaptonemal complexes (SCs) is an essential feature of meiosis. In many organisms, synapsis and homologous recombination are interdependent: recombination promotes SC formation and SCs are required for crossing-over. Moreover, sever...

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Detalles Bibliográficos
Autores principales: Qiao, Huanyu, Chen, Jefferson K., Reynolds, April, Höög, Christer, Paddy, Michael, Hunter, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386176/
https://www.ncbi.nlm.nih.gov/pubmed/22761591
http://dx.doi.org/10.1371/journal.pgen.1002790