Dengue Virus Targets the Adaptor Protein MITA to Subvert Host Innate Immunity

Dengue is one of the most important arboviral diseases caused by infection of four serotypes of dengue virus (DEN). We found that activation of interferon regulatory factor 3 (IRF3) triggered by viral infection and by foreign DNA and RNA stimulation was blocked by DEN-encoded NS2B3 through a proteas...

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Detalles Bibliográficos
Autores principales: Yu, Chia-Yi, Chang, Tsung-Hsien, Liang, Jian-Jong, Chiang, Ruei-Lin, Lee, Yi-Ling, Liao, Ching-Len, Lin, Yi-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386177/
https://www.ncbi.nlm.nih.gov/pubmed/22761576
http://dx.doi.org/10.1371/journal.ppat.1002780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386177/
https://www.ncbi.nlm.nih.gov/pubmed/22761576
http://dx.doi.org/10.1371/journal.ppat.1002780

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