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Equation-Free Analysis of Two-Component System Signalling Model Reveals the Emergence of Co-Existing Phenotypes in the Absence of Multistationarity

Phenotypic differences of genetically identical cells under the same environmental conditions have been attributed to the inherent stochasticity of biochemical processes. Various mechanisms have been suggested, including the existence of alternative steady states in regulatory networks that are reac...

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Detalles Bibliográficos
Autores principales: Hoyle, Rebecca B., Avitabile, Daniele, Kierzek, Andrzej M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386199/
https://www.ncbi.nlm.nih.gov/pubmed/22761552
http://dx.doi.org/10.1371/journal.pcbi.1002396