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Regional Heterogeneity in Murine Lung Fibroblasts from Normal Mice or Mice Exposed Once to Cigarette Smoke

Chronic obstructive lung disease (COPD) is characterized by matrix deposition in the small airways but matrix loss from the parenchyma, phenomena which must depend on the ability of local fibroblasts to produce matrix after smoke exposure. To investigate this idea, we exposed C57Bl/6 mice once to ci...

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Detalles Bibliográficos
Autores principales: Preobrazhenska, Olena, Wright, Joanne L., Churg, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386200/
https://www.ncbi.nlm.nih.gov/pubmed/22761892
http://dx.doi.org/10.1371/journal.pone.0039761