Endoglin regulates PI3-kinase/Akt trafficking and signaling to alter endothelial capillary stability during angiogenesis

Endoglin (CD105) is an endothelial-specific transforming growth factor β (TGF-β) coreceptor essential for angiogenesis and vascular homeostasis. Although endoglin dysfunction contributes to numerous vascular conditions, the mechanism of endoglin action remains poorly understood. Here we report a nov...

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Detalles Bibliográficos
Autores principales: Lee, Nam Y., Golzio, Christelle, Gatza, Catherine E., Sharma, Arun, Katsanis, Nicholas, Blobe, Gerard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386206/
https://www.ncbi.nlm.nih.gov/pubmed/22593212
http://dx.doi.org/10.1091/mbc.E11-12-0993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386206/
https://www.ncbi.nlm.nih.gov/pubmed/22593212
http://dx.doi.org/10.1091/mbc.E11-12-0993

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