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A role for myosin IXb, a motor–RhoGAP chimera, in epithelial wound healing and tight junction regulation
Polymorphisms in the gene encoding the heavy chain of myosin IXb (Myo9b) have been linked to several forms of inflammatory bowel disease (IBD). Given that Myo9b contains a RhoGTPase-activating protein domain within its tail, it may play key roles in Rho-mediated actin cytoskeletal modifications crit...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The American Society for Cell Biology
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386211/ https://www.ncbi.nlm.nih.gov/pubmed/22573889 http://dx.doi.org/10.1091/mbc.E11-09-0803 |