Cargando…

Rab GTPase regulation of retromer-mediated cargo export during endosome maturation

The retromer complex, composed of sorting nexin subunits and a Vps26/Vps29/Vps35 trimer, mediates sorting of retrograde cargo from the endosome to the trans-Golgi network. The retromer trimer subcomplex is an effector of Rab7 (Ypt7 in yeast). Whereas endosome targeting of human retromer has been sho...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Ting-Ting, Gomez, Timothy S., Sackey, Bridget K., Billadeau, Daniel D., Burd, Christopher G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386214/
https://www.ncbi.nlm.nih.gov/pubmed/22593205
http://dx.doi.org/10.1091/mbc.E11-11-0915