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Local control of phosphatidylinositol 4-phosphate signaling in the Golgi apparatus by Vps74 and Sac1 phosphoinositide phosphatase

In the Golgi apparatus, lipid homeostasis pathways are coordinated with the biogenesis of cargo transport vesicles by phosphatidylinositol 4-kinases (PI4Ks) that produce phosphatidylinositol 4-phosphate (PtdIns4P), a signaling molecule that is recognized by downstream effector proteins. Quantitative...

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Detalles Bibliográficos
Autores principales: Wood, Christopher S., Hung, Chia-Sui, Huoh, Yu-San, Mousley, Carl J., Stefan, Christopher J., Bankaitis, Vytas, Ferguson, Kathryn M., Burd, Christopher G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386216/
https://www.ncbi.nlm.nih.gov/pubmed/22553352
http://dx.doi.org/10.1091/mbc.E12-01-0077