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The inositol 5-phosphatase SHIP2 is an effector of RhoA and is involved in cell polarity and migration
Cell migration is essential for various physiological and pathological processes. Polarization in motile cells requires the coordination of several key signaling molecules, including RhoA small GTPases and phosphoinositides. Although RhoA participates in a front–rear polarization in migrating cells,...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386222/ https://www.ncbi.nlm.nih.gov/pubmed/22593208 http://dx.doi.org/10.1091/mbc.E11-11-0958 |