Distinct roles of mitochondria- and ER-localized Bcl-x(L) in apoptosis resistance and Ca(2+) homeostasis

Bcl-2 proteins are major regulators of cellular responses to intrinsic and extrinsic apoptotic stimuli. Among them, overexpression of the antiapoptotic protein Bcl-x(L) modulates intracellular Ca(2+) homeostasis and organelle-specific apoptotic signaling pathways. However, the specific activities of...

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Detalles Bibliográficos
Autores principales: Eno, Colins O., Eckenrode, Emily F., Olberding, Kristen E., Zhao, Guoping, White, Carl, Li, Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386223/
https://www.ncbi.nlm.nih.gov/pubmed/22573883
http://dx.doi.org/10.1091/mbc.E12-02-0090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386223/
https://www.ncbi.nlm.nih.gov/pubmed/22573883
http://dx.doi.org/10.1091/mbc.E12-02-0090

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