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Aldosterone Antagonists in Monotherapy Are Protective against Streptozotocin-Induced Diabetic Nephropathy in Rats

Angiotensin converting enzyme inhibitors (ACEi) and angiotensin II receptor blockers (ARB) are the standard clinical therapy of diabetic nephropathy (DN), while aldosterone antagonists are only used as adjuncts. Previously in experimental DN we showed that Na/K ATPase (NKA) is mislocated and angiote...

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Detalles Bibliográficos
Autores principales: Banki, Nora F., Ver, Agota, Wagner, Laszlo J., Vannay, Adam, Degrell, Peter, Prokai, Agnes, Gellai, Renata, Lenart, Lilla, Szakal, Dorottya-Nagy, Kenesei, Eva, Rosta, Klara, Reusz, Gyorgy, Szabo, Attila J., Tulassay, Tivadar, Baylis, Chris, Fekete, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386228/
https://www.ncbi.nlm.nih.gov/pubmed/22761931
http://dx.doi.org/10.1371/journal.pone.0039938