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Quantifying the Adaptive Potential of an Antibiotic Resistance Enzyme
For a quantitative understanding of the process of adaptation, we need to understand its “raw material,” that is, the frequency and fitness effects of beneficial mutations. At present, most empirical evidence suggests an exponential distribution of fitness effects of beneficial mutations, as predict...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386231/ https://www.ncbi.nlm.nih.gov/pubmed/22761587 http://dx.doi.org/10.1371/journal.pgen.1002783 |