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Quantifying the Adaptive Potential of an Antibiotic Resistance Enzyme

For a quantitative understanding of the process of adaptation, we need to understand its “raw material,” that is, the frequency and fitness effects of beneficial mutations. At present, most empirical evidence suggests an exponential distribution of fitness effects of beneficial mutations, as predict...

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Detalles Bibliográficos
Autores principales: Schenk, Martijn F., Szendro, Ivan G., Krug, Joachim, de Visser, J. Arjan G. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386231/
https://www.ncbi.nlm.nih.gov/pubmed/22761587
http://dx.doi.org/10.1371/journal.pgen.1002783

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