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Learning and Nicotine Interact to Increase CREB Phosphorylation at the jnk1 Promoter in the Hippocampus

Nicotine is known to enhance long-term hippocampus dependent learning and memory in both rodents and humans via its activity at nicotinic acetylcholinergic receptors (nAChRs). However, the molecular basis for the nicotinic modulation of learning is incompletely understood. Both the mitogen activated...

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Detalles Bibliográficos
Autores principales: Kenney, Justin W., Poole, Rachel L., Adoff, Michael D., Logue, Sheree F., Gould, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386232/
https://www.ncbi.nlm.nih.gov/pubmed/22761932
http://dx.doi.org/10.1371/journal.pone.0039939