Mutagenesis-Mediated Decrease of Pathogenicity as a Feature of the Mutant Spectrum of a Viral Population

BACKGROUND: RNA virus populations are heterogeneous ensembles of closely related genomes termed quasispecies. This highly complex distribution of variants confers important properties to RNA viruses and influences their pathogenic behavior. It has been hypothesized that increased mutagenesis of vira...

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Detalles Bibliográficos
Autores principales: Sanz-Ramos, Marta, Rodríguez-Calvo, Teresa, Sevilla, Noemí
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386257/
https://www.ncbi.nlm.nih.gov/pubmed/22761933
http://dx.doi.org/10.1371/journal.pone.0039941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386257/
https://www.ncbi.nlm.nih.gov/pubmed/22761933
http://dx.doi.org/10.1371/journal.pone.0039941

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