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IL-4 Engagement of the Type I IL-4 Receptor Complex Enhances Mouse Eosinophil Migration to Eotaxin-1 In Vitro

BACKGROUND: Previous work from our laboratory demonstrated that IL-4Rα expression on a myeloid cell type was responsible for enhancement of Th2-driven eosinophilic inflammation in a mouse model of allergic lung inflammation. Subsequently, we have shown that IL-4 signaling through type I IL-4 recepto...

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Detalles Bibliográficos
Autores principales: Heller, Nicola M., Gwinn, William M., Donnelly, Raymond P., Constant, Stephanie L., Keegan, Achsah D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386270/
https://www.ncbi.nlm.nih.gov/pubmed/22761864
http://dx.doi.org/10.1371/journal.pone.0039673