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IL-4 Engagement of the Type I IL-4 Receptor Complex Enhances Mouse Eosinophil Migration to Eotaxin-1 In Vitro
BACKGROUND: Previous work from our laboratory demonstrated that IL-4Rα expression on a myeloid cell type was responsible for enhancement of Th2-driven eosinophilic inflammation in a mouse model of allergic lung inflammation. Subsequently, we have shown that IL-4 signaling through type I IL-4 recepto...
Autores principales: | Heller, Nicola M., Gwinn, William M., Donnelly, Raymond P., Constant, Stephanie L., Keegan, Achsah D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386270/ https://www.ncbi.nlm.nih.gov/pubmed/22761864 http://dx.doi.org/10.1371/journal.pone.0039673 |
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