Line-Tension Controlled Mechanism for Influenza Fusion

Our molecular simulations reveal that wild-type influenza fusion peptides are able to stabilize a highly fusogenic pre-fusion structure, i.e. a peptide bundle formed by four or more trans-membrane arranged fusion peptides. We rationalize that the lipid rim around such bundle has a non-vanishing rim...

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Detalles Bibliográficos
Autores principales: Risselada, Herre Jelger, Marelli, Giovanni, Fuhrmans, Marc, Smirnova, Yuliya G., Grubmüller, Helmut, Marrink, Siewert Jan, Müller, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386277/
https://www.ncbi.nlm.nih.gov/pubmed/22761674
http://dx.doi.org/10.1371/journal.pone.0038302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386277/
https://www.ncbi.nlm.nih.gov/pubmed/22761674
http://dx.doi.org/10.1371/journal.pone.0038302

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