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Line-Tension Controlled Mechanism for Influenza Fusion
Our molecular simulations reveal that wild-type influenza fusion peptides are able to stabilize a highly fusogenic pre-fusion structure, i.e. a peptide bundle formed by four or more trans-membrane arranged fusion peptides. We rationalize that the lipid rim around such bundle has a non-vanishing rim...
Autores principales: | Risselada, Herre Jelger, Marelli, Giovanni, Fuhrmans, Marc, Smirnova, Yuliya G., Grubmüller, Helmut, Marrink, Siewert Jan, Müller, Marcus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386277/ https://www.ncbi.nlm.nih.gov/pubmed/22761674 http://dx.doi.org/10.1371/journal.pone.0038302 |
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