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Pattern, and not magnitude, of neural activity determines dendritic spine stability in awake mice

The stability of dendritic spines in the neocortex is profoundly influenced by sensory experience, which determines the magnitude and pattern of neural firing. By optically manipulating the temporal structure of neural activity in vivo using channelrhodopsin-2 and repeatedly imaging dendritic spines...

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Detalles Bibliográficos
Autores principales: Wyatt, Ryan M., Tring, Elaine, Trachtenberg, Joshua T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386353/
https://www.ncbi.nlm.nih.gov/pubmed/22706266
http://dx.doi.org/10.1038/nn.3134