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Recombinant tissue plasminogen activator for acute ischaemic stroke: an updated systematic review and meta-analysis

BACKGROUND: Recombinant tissue plasminogen activator (rt-PA, alteplase) improved functional outcome in patients treated soon after acute ischaemic stroke in randomised trials, but licensing is restrictive and use varies widely. The IST-3 trial adds substantial new data. We therefore assessed all the...

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Detalles Bibliográficos
Autores principales: Wardlaw, Joanna M, Murray, Veronica, Berge, Eivind, del Zoppo, Gregory, Sandercock, Peter, Lindley, Richard L, Cohen, Geoff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lancet Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386494/
https://www.ncbi.nlm.nih.gov/pubmed/22632907
http://dx.doi.org/10.1016/S0140-6736(12)60738-7