Predicting protein-protein interface residues using local surface structural similarity

BACKGROUND: Identification of the residues in protein-protein interaction sites has a significant impact in problems such as drug discovery. Motivated by the observation that the set of interface residues of a protein tend to be conserved even among remote structural homologs, we introduce PrISE, a...

Descripción completa

Detalles Bibliográficos
Autores principales: Jordan, Rafael A, EL-Manzalawy, Yasser, Dobbs, Drena, Honavar, Vasant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386866/
https://www.ncbi.nlm.nih.gov/pubmed/22424103
http://dx.doi.org/10.1186/1471-2105-13-41

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386866/
https://www.ncbi.nlm.nih.gov/pubmed/22424103
http://dx.doi.org/10.1186/1471-2105-13-41

Ejemplares similares