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Predicting protein-protein interface residues using local surface structural similarity
BACKGROUND: Identification of the residues in protein-protein interaction sites has a significant impact in problems such as drug discovery. Motivated by the observation that the set of interface residues of a protein tend to be conserved even among remote structural homologs, we introduce PrISE, a...
Autores principales: | Jordan, Rafael A, EL-Manzalawy, Yasser, Dobbs, Drena, Honavar, Vasant |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386866/ https://www.ncbi.nlm.nih.gov/pubmed/22424103 http://dx.doi.org/10.1186/1471-2105-13-41 |
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