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Chemoresistance in Prostate Cancer Cells Is Regulated by miRNAs and Hedgehog Pathway

Many prostate cancers relapse due to the generation of chemoresistance rendering first-line treatment drugs like paclitaxel (PTX) ineffective. The present study aims to determine the role of miRNAs and Hedgehog (Hh) pathway in chemoresistant prostate cancer and to evaluate the combination therapy us...

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Detalles Bibliográficos
Autores principales: Singh, Saurabh, Chitkara, Deepak, Mehrazin, Reza, Behrman, Stephen W., Wake, Robert W., Mahato, Ram I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386918/
https://www.ncbi.nlm.nih.gov/pubmed/22768203
http://dx.doi.org/10.1371/journal.pone.0040021