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Clinicopathological Significance and Prognostic Value of DNA Methyltransferase 1, 3a, and 3b Expressions in Sporadic Epithelial Ovarian Cancer

Altered DNA methylation of tumor suppressor gene promoters plays a role in human carcinogenesis and DNA methyltransferases (DNMTs) are responsible for it. This study aimed to determine aberrant expression of DNMT1, DNMT3a, and DNMT3b in benign and malignant ovarian tumor tissues for their associatio...

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Detalles Bibliográficos
Autores principales: Bai, Xuefeng, Song, Zhiguo, Fu, Yingzi, Yu, Zhaojin, Zhao, Lin, Zhao, Haishan, Yao, Weifan, Huang, Desheng, Mi, Xiaoyi, Wang, Enhua, Zheng, Zhihong, Wei, Minjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386927/
https://www.ncbi.nlm.nih.gov/pubmed/22768205
http://dx.doi.org/10.1371/journal.pone.0040024