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A FRET-Based High Throughput Screening Assay to Identify Inhibitors of Anthrax Protective Antigen Binding to Capillary Morphogenesis Gene 2 Protein

Anti-angiogenic therapies are effective for the treatment of cancer, a variety of ocular diseases, and have potential benefits in cardiovascular disease, arthritis, and psoriasis. We have previously shown that anthrax protective antigen (PA), a non-pathogenic component of anthrax toxin, is an inhibi...

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Detalles Bibliográficos
Autores principales: Rogers, Michael S., Cryan, Lorna M., Habeshian, Kaiane A., Bazinet, Lauren, Caldwell, Thomas P., Ackroyd, P. Christine, Christensen, Kenneth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386954/
https://www.ncbi.nlm.nih.gov/pubmed/22768167
http://dx.doi.org/10.1371/journal.pone.0039911