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A FRET-Based High Throughput Screening Assay to Identify Inhibitors of Anthrax Protective Antigen Binding to Capillary Morphogenesis Gene 2 Protein
Anti-angiogenic therapies are effective for the treatment of cancer, a variety of ocular diseases, and have potential benefits in cardiovascular disease, arthritis, and psoriasis. We have previously shown that anthrax protective antigen (PA), a non-pathogenic component of anthrax toxin, is an inhibi...
Autores principales: | Rogers, Michael S., Cryan, Lorna M., Habeshian, Kaiane A., Bazinet, Lauren, Caldwell, Thomas P., Ackroyd, P. Christine, Christensen, Kenneth A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386954/ https://www.ncbi.nlm.nih.gov/pubmed/22768167 http://dx.doi.org/10.1371/journal.pone.0039911 |
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