Huntingtin Fragments and SOD1 Mutants Form Soluble Oligomers in the Cell

Diffusion coefficients of huntingtin (Htt) fragments and SOD1 mutants expressed in cells were measured using fluorescence correlation spectroscopy. The diffusion mobilities of both non-pathological Htt fragments (25 polyQs) and pathological Htt fragments (103 polyQs) were much slower than expected f...

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Detalles Bibliográficos
Autores principales: Park, Yang-Nim, Zhao, Xiaohong, Norton, Mark, Taylor, J. Paul, Eisenberg, Evan, Greene, Lois E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386994/
https://www.ncbi.nlm.nih.gov/pubmed/22768276
http://dx.doi.org/10.1371/journal.pone.0040329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386994/
https://www.ncbi.nlm.nih.gov/pubmed/22768276
http://dx.doi.org/10.1371/journal.pone.0040329

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