Engineering Yarrowia lipolytica to Produce Glycoproteins Homogeneously Modified with the Universal Man(3)GlcNAc(2) N-Glycan Core

Yarrowia lipolytica is a dimorphic yeast that efficiently secretes various heterologous proteins and is classified as “generally recognized as safe.” Therefore, it is an attractive protein production host. However, yeasts modify glycoproteins with non-human high mannose-type N-glycans. These structu...

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Detalles Bibliográficos
Autores principales: De Pourcq, Karen, Tiels, Petra, Van Hecke, Annelies, Geysens, Steven, Vervecken, Wouter, Callewaert, Nico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386995/
https://www.ncbi.nlm.nih.gov/pubmed/22768188
http://dx.doi.org/10.1371/journal.pone.0039976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386995/
https://www.ncbi.nlm.nih.gov/pubmed/22768188
http://dx.doi.org/10.1371/journal.pone.0039976

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