Cargando…
Engineering Yarrowia lipolytica to Produce Glycoproteins Homogeneously Modified with the Universal Man(3)GlcNAc(2) N-Glycan Core
Yarrowia lipolytica is a dimorphic yeast that efficiently secretes various heterologous proteins and is classified as “generally recognized as safe.” Therefore, it is an attractive protein production host. However, yeasts modify glycoproteins with non-human high mannose-type N-glycans. These structu...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386995/ https://www.ncbi.nlm.nih.gov/pubmed/22768188 http://dx.doi.org/10.1371/journal.pone.0039976 |