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A MicroRNA-7 Binding Site Polymorphism in HOXB5 Leads to Differential Gene Expression in Bladder Cancer

PURPOSE: To investigate the biological function of HOXB5 in human bladder cancer and explore whether the HOXB5 3′-UTR SNP (1010A/G), which is located within the microRNA-7 binding site, was correlated with clinical features of bladder cancer. METHODS: Expression of HOXB5 in 35 human bladder cancer t...

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Detalles Bibliográficos
Autores principales: Luo, Junhua, Cai, Qingqing, Wang, Wei, Huang, Hui, Zeng, Hong, He, Wang, Deng, Weixi, Yu, Hao, Chan, Eddie, NG, Chi-fai, Huang, Jian, Lin, Tianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387002/
https://www.ncbi.nlm.nih.gov/pubmed/22768238
http://dx.doi.org/10.1371/journal.pone.0040127