Nicotinamide Phosphoribosyl Transferase (Nampt) Is Required for De Novo Lipogenesis in Tumor Cells

Tumor cells have increased metabolic requirements to maintain rapid growth. In particular, a highly lipogenic phenotype is a hallmark of many tumor types, including prostate. Cancer cells also have increased turnover of nicotinamide adenine dinucleotide (NAD(+)), a coenzyme involved in multiple meta...

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Detalles Bibliográficos
Autores principales: Bowlby, Sarah C., Thomas, Michael J., D’Agostino, Ralph B., Kridel, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387004/
https://www.ncbi.nlm.nih.gov/pubmed/22768255
http://dx.doi.org/10.1371/journal.pone.0040195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387004/
https://www.ncbi.nlm.nih.gov/pubmed/22768255
http://dx.doi.org/10.1371/journal.pone.0040195

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