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Y1 and Y5 Receptors Are Both Required for the Regulation of Food Intake and Energy Homeostasis in Mice

Neuropeptide Y (NPY) acting in the hypothalamus is one of the most powerful orexigenic agents known. Of the five known Y receptors, hypothalamic Y1 and Y5 have been most strongly implicated in mediating hyperphagic effects. However, knockout of individual Y1 or Y5 receptors induces late-onset obesit...

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Detalles Bibliográficos
Autores principales: Nguyen, Amy D., Mitchell, Natalie F., Lin, Shu, Macia, Laurence, Yulyaningsih, Ernie, Baldock, Paul A., Enriquez, Ronaldo F., Zhang, Lei, Shi, Yan-Chuan, Zolotukhin, Serge, Herzog, Herbert, Sainsbury, Amanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387009/
https://www.ncbi.nlm.nih.gov/pubmed/22768253
http://dx.doi.org/10.1371/journal.pone.0040191