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Sensing of Fatty Acids for Octanoylation of Ghrelin Involves a Gustatory G-Protein

BACKGROUND: Ghrelin is an important regulator of energy – and glucose homeostasis. The octanoylation at Ser(3) is essential for ghrelin’s biological effects but the mechanisms involved in the octanoylation are unknown. We investigated whether the gustatory G-protein, α-gustducin, and the free fatty...

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Detalles Bibliográficos
Autores principales: Janssen, Sara, Laermans, Jorien, Iwakura, Hiroshi, Tack, Jan, Depoortere, Inge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387020/
https://www.ncbi.nlm.nih.gov/pubmed/22768248
http://dx.doi.org/10.1371/journal.pone.0040168