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Sensing of Fatty Acids for Octanoylation of Ghrelin Involves a Gustatory G-Protein
BACKGROUND: Ghrelin is an important regulator of energy – and glucose homeostasis. The octanoylation at Ser(3) is essential for ghrelin’s biological effects but the mechanisms involved in the octanoylation are unknown. We investigated whether the gustatory G-protein, α-gustducin, and the free fatty...
Autores principales: | Janssen, Sara, Laermans, Jorien, Iwakura, Hiroshi, Tack, Jan, Depoortere, Inge |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387020/ https://www.ncbi.nlm.nih.gov/pubmed/22768248 http://dx.doi.org/10.1371/journal.pone.0040168 |
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