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Neuroprotection of Tanshinone IIA against Cerebral Ischemia/Reperfusion Injury through Inhibition of Macrophage Migration Inhibitory Factor in Rats

BACKGROUND: Ischemia/reperfusion (I/R) injury is associated with systemic inflammatory response. Macrophage migration inhibitory factor (MIF) has been implicated in many inflammatory processes. Tanshinone IIA (TSA) is one of the active ingredients in danshen, which derived from the dried root or rhi...

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Detalles Bibliográficos
Autores principales: Chen, Yanlin, Wu, Xuemei, Yu, Shanshan, Lin, Xuemei, Wu, Jingxian, Li, Lan, Zhao, Jing, Zhao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387137/
https://www.ncbi.nlm.nih.gov/pubmed/22768247
http://dx.doi.org/10.1371/journal.pone.0040165