The Chromosome 9p21.3 Coronary Heart Disease Risk Allele Is Associated with Altered Gene Expression in Normal Heart and Vascular Tissues

Genome-wide association studies have identified a coronary artery disease (CAD) risk locus in a non-coding region at 9p21.3, the nearest genes being CDKN2A and CDKN2B. To understand the pathways by which this locus might influence CAD susceptibility, we investigated associations between the 9p21.3 r...

Descripción completa

Detalles Bibliográficos
Autores principales: Pilbrow, Anna P., Folkersen, Lasse, Pearson, John F., Brown, Chris M., McNoe, Les, Wang, Nancy M., Sweet, Wendy E., Tang, W. H. Wilson, Black, Michael A., Troughton, Richard W., Richards, A. Mark, Franco-Cereceda, Anders, Gabrielsen, Anders, Eriksson, Per, Moravec, Christine S., Cameron, Vicky A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387158/
https://www.ncbi.nlm.nih.gov/pubmed/22768093
http://dx.doi.org/10.1371/journal.pone.0039574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387158/
https://www.ncbi.nlm.nih.gov/pubmed/22768093
http://dx.doi.org/10.1371/journal.pone.0039574

Ejemplares similares