Intramolecular Epistasis and the Evolution of a New Enzymatic Function

Atrazine chlorohydrolase (AtzA) and its close relative melamine deaminase (TriA) differ by just nine amino acid substitutions but have distinct catalytic activities. Together, they offer an informative model system to study the molecular processes that underpin the emergence of new enzymatic functio...

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Detalles Bibliográficos
Autores principales: Noor, Sajid, Taylor, Matthew C., Russell, Robyn J., Jermiin, Lars S., Jackson, Colin J., Oakeshott, John G., Scott, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387218/
https://www.ncbi.nlm.nih.gov/pubmed/22768133
http://dx.doi.org/10.1371/journal.pone.0039822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387218/
https://www.ncbi.nlm.nih.gov/pubmed/22768133
http://dx.doi.org/10.1371/journal.pone.0039822

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