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MMP-15 Is Upregulated in Preeclampsia, but Does Not Cleave Endoglin to Produce Soluble Endoglin

Preeclampsia is a major pregnancy complication, characterized by severe endothelial dysfunction, hypertension and maternal end-organ damage. Soluble endoglin is an anti-angiogenic protein released from placenta and thought to play a central role in causing the endothelial dysfunction and maternal or...

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Detalles Bibliográficos
Autores principales: Kaitu’u-Lino, Tu’uhevaha J., Palmer, Kirsten, Tuohey, Laura, Ye, Louie, Tong, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387233/
https://www.ncbi.nlm.nih.gov/pubmed/22768148
http://dx.doi.org/10.1371/journal.pone.0039864