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Relaxation of Adaptive Evolution during the HIV-1 Infection Owing to Reduction of CD4+ T Cell Counts

BACKGROUND: The first stages of HIV-1 infection are essential to establish the diversity of virus population within host. It has been suggested that adaptation to host cells and antibody evasion are the leading forces driving HIV evolution at the initial stages of AIDS infection. In order to gain mo...

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Detalles Bibliográficos
Autores principales: Leal, Élcio, Casseb, Jorge, Hendry, Michael, Busch, Michael P., Diaz, Ricardo Sobhie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387245/
https://www.ncbi.nlm.nih.gov/pubmed/22768122
http://dx.doi.org/10.1371/journal.pone.0039776