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Relaxation of Adaptive Evolution during the HIV-1 Infection Owing to Reduction of CD4+ T Cell Counts
BACKGROUND: The first stages of HIV-1 infection are essential to establish the diversity of virus population within host. It has been suggested that adaptation to host cells and antibody evasion are the leading forces driving HIV evolution at the initial stages of AIDS infection. In order to gain mo...
Autores principales: | Leal, Élcio, Casseb, Jorge, Hendry, Michael, Busch, Michael P., Diaz, Ricardo Sobhie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387245/ https://www.ncbi.nlm.nih.gov/pubmed/22768122 http://dx.doi.org/10.1371/journal.pone.0039776 |
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